After saving virologist Dr. Charlotte Fox from a vicious attack in the mountains outside Los Angeles, a mine-dwelling recluse named Mango learns a virus has swept the globe causing a worldwide zombie outbreak. In order to continue her work on the vaccine, Dr. Fox must find her uncle whose last known whereabouts were 100 miles away in Joshua Tree. Mango, Dr. Fox and Mango's dog Kismet embark on a dangerous journey to find Dr. Fox's uncle and complete the vaccine all while Mango's mysterious past comes to light.